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1

CA2+ Tides in Cardiomyocytes Under Mechanical Loading

Jian, Zhong, Izu, Leighton T, Chen, Yi-Je, Wood, Brittani, Bossuyt, Julie, Lam, Kit S, Chen-Izu, Ye

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 48 KB

english, 2016

2

Altered Repolarization Reserve in Failing Rabbit Ventricular Myocytes

Hegyi, Bence, Bossuyt, Julie, Ginsburg, Kenneth S., Mendoza, Lynette M., Talken, Linda, Ferrier, William T., Pogwizd, Steven M., Izu, Leighton T., Chen-Izu, Ye, Bers, Donald M.

Journal:

Circulation Arrhythmia and Electrophysiology

Year:

2018

Language:

english

File:

PDF, 2.57 MB

english, 2018

3

Balance Between Rapid Delayed Rectifier K + Current and Late Na + Current on Ventricular Repolarization: An Effective Antiarrhythmic Target?

Hegyi, Bence, Chen-Izu, Ye, Izu, Leighton T., Rajamani, Sridharan, Belardinelli, Luiz, Bers, Donald M., BÃ¡nyÃ¡sz, TamÃ¡s

Journal:

Circulation Arrhythmia and Electrophysiology

Year:

2020

Language:

english

File:

PDF, 2.55 MB

english, 2020

4

A memory-efficient finite element method for systems of reaction–diffusion equations with non-smooth forcing

Alexander L. Hanhart, Matthias K. Gobbert, Leighton T. Izu

Journal:

Journal of Computational and Applied Mathematics

Year:

2004

Language:

english

File:

PDF, 644 KB

english, 2004

5

Transformation of adult rat cardiac myocytes in primary culture

Tamas Banyasz, Ilya Lozinskiy, Charles E. Payne, Stephanie Edelmann, Byron Norton, Biyi Chen, Ye Chen-Izu, Leighton T. Izu, C. William Balke

Journal:

Experimental Physiology

Year:

2008

Language:

english

File:

PDF, 895 KB

english, 2008

6

Role of the Transverse-Axial Tubule System in Generating Calcium Sparks and Calcium Transients in Rat Atrial Myocytes

Malcolm M. Kirk, Leighton T. Izu, Ye Chen-Izu, Stacey L. McCulle, W. Gil Wier, C. William Balke, Stephen R. Shorofsky

Journal:

The Journal of Physiology

Year:

2003

Language:

english

File:

PDF, 1.33 MB

english, 2003

7

Calcium Handling in Human Embryonic Stem Cell-Derived Cardiomyocytes

Jonathan Satin, Ilanit Itzhaki, Sophia Rapoport, Elizabeth A. Schroder, Leighton Izu, Gil Arbel, Rafael Beyar, C. William Balke, Jackie Schiller, Lior Gepstein

Journal:

Year:

2008

Language:

english

File:

PDF, 4.44 MB

english, 2008

8

Sequential dissection of multiple ionic currents in single cardiac myocytes under action potential-clamp

Tamas Banyasz, Balazs Horvath, Zhong Jian, Leighton T. Izu, Ye Chen-Izu

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2011

Language:

english

File:

PDF, 765 KB

english, 2011

9

Une cellule type?

Leighton T. Izu, Ye Chen-Izu

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2012

Language:

english

File:

PDF, 131 KB

english, 2012

10

Gi-Dependent Localization of β2-Adrenergic Receptor Signaling to L-Type Ca2+ Channels

Chen-Izu, Ye, Xiao, Rui-Ping, Izu, Leighton T., Cheng, Heping, Kuschel, Meike, Spurgeon, Harold, Lakatta, Edward G.

Journal:

Biophysical Journal

Year:

2000

Language:

english

File:

PDF, 172 KB

english, 2000

11

Large Currents Generate Cardiac Ca2+ Sparks

Izu, Leighton T., Mauban, Joseph R.H., Balke, C.W., Wier, W. Gil

Journal:

Biophysical Journal

Year:

2001

Language:

english

File:

PDF, 323 KB

english, 2001

12

Evolution of Cardiac Calcium Waves from Stochastic Calcium Sparks

Izu, Leighton T., Wier, W. Gil, Balke, C. William

Journal:

Biophysical Journal

Year:

2001

Language:

english

File:

PDF, 632 KB

english, 2001

13

CaMKII Regulates L-type Ca2+ Current during Action Potential Plateau and Repolarization _ a Direct Link to Arrhythmias

Banyasz, Tamas, Izu, Leighton T., Chen-Izu, Ye

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 72 KB

english, 2009

14

Cellular Cartography

Chen-Izu, Ye, Izu, Leighton T.

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 47 KB

english, 2010

15

Changes in Ca2+/Calmodulin-Dependent Protein Kinase (CaMKII) During Development of Hypertension-Induced Hypertrophy and Heart Failure

Yu, David, Bossuyt, Julie, Erickson, Jeffery, Norton, Byron, Sumandea, Marius P., Izu, Leighton T., Bers, Donald M., Chen-Izu, Ye

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 58 KB

english, 2011

16

Profile of L-Type Ca2+ Current and Na+/Ca2+ Exchange Current during Cardiac Action Potential in Ventricular Myocytes

Banyasz, Tamas, Horvath, Balazs, Jian, Zhong, Izu, Leighton T., Chen-Izy, Ye

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 44 KB

english, 2012

17

Theoretical Analysis of the Ca2+ Spark Amplitude Distribution

Izu, Leighton T., Gil Wier, W., William Balke, C.

Journal:

Biophysical Journal

Year:

1998

Language:

english

File:

PDF, 585 KB

english, 1998

18

Three-Dimensional Distribution of Ryanodine Receptor Clusters in Cardiac Myocytes

Chen-Izu, Ye, McCulle, Stacey L., Ward, Chris W., Soeller, Christian, Allen, Bryan M., Rabang, Cal, Cannell, Mark B., Balke, C. William, Izu, Leighton T.

Journal:

Biophysical Journal

Year:

2006

Language:

english

File:

PDF, 719 KB

english, 2006

19

Interplay of Ryanodine Receptor Distribution and Calcium Dynamics

Izu, Leighton T., Means, Shawn A., Shadid, John N., Chen-Izu, Ye, Balke, C. William

Journal:

Biophysical Journal

Year:

2006

Language:

english

File:

PDF, 713 KB

english, 2006

20

A New Approach to the Detection and Statistical Classification of Ca2+ Sparks

Bányász, Tamás, Chen-Izu, Ye, Balke, C.W., Izu, Leighton T.

Journal:

Biophysical Journal

Year:

2007

Language:

english

File:

PDF, 298 KB

english, 2007

21

Eavesdropping on the Social Lives of Ca2+ Sparks

Izu, Leighton T., Bányász, Tamás, Balke, C. William, Chen-Izu, Ye

Journal:

Biophysical Journal

Year:

2007

Language:

english

File:

PDF, 397 KB

english, 2007

22

Dynamics of the late Na+ current during cardiac action potential and its contribution to afterdepolarizations

Horvath, Balazs, Banyasz, Tamas, Jian, Zhong, Hegyi, Bence, Kistamas, Kornel, Nanasi, Peter P., Izu, Leighton T., Chen-Izu, Ye

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2013

Language:

english

File:

PDF, 564 KB

english, 2013

23

Beta-adrenergic stimulation reverses theIKr–IKsdominant pattern during cardiac action potential

Banyasz, Tamas, Jian, Zhong, Horvath, Balazs, Khabbaz, Shaden, Izu, Leighton T., Chen-Izu, Ye

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2014

Language:

english

File:

PDF, 732 KB

english, 2014

24

Ca2+ waves in the heart

Izu, Leighton T., Xie, Yuanfang, Sato, Daisuke, Bányász, Tamás, Chen-Izu, Ye

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2013

Language:

english

File:

PDF, 381 KB

english, 2013

25

Optimal Reticulated Coverage of the Sarcoplasmic Reticulum

Coulibaly, Zana A., Izu, Leighton T., Peercy, Bradford E.

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 64 KB

english, 2014

26

CaMKII Regulation of the Dynamic L-Type Ca2+ Current and Na+/Ca2+ Exchange Current During Action Potential in Cardiac Myocytes

Banyasz, Tamas, Izu, Leighton T., Chen-Izu, Ye

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 85 KB

english, 2010

27

Cell Edge Detector: Recovering Length Information from Line-Scan Confocal Images

Puglisi, Jose L., Izu, Leighton T., Chen-Izu, Ye, Bers, Donald M.

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 72 KB

english, 2013

28

Individual Cell Electrophysiology (ICE) of Cardiac Myocytes _ Using Innovative ‘Onion-Peeling’ Technique to Study the ICE of Excitable Cells

Banyasz, Tamas, Jian, Zhong, Horvath, Balazs, Izu, Leighton T., Chen-Izu, Ye

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 44 KB

english, 2012

29

Feed Forward Modeling. Fixing the Force Frequency Relationship

Puglisi, Jose L., Izu, Leighton, Chen-Izu, Ye, Bers, Donald M.

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 54 KB

english, 2012

30

Dynamic Late Na Current During Cardiac Action Potential Revealed by a Specific and Potent Inhibitor Gs967

Jian, Zhong, Horvath, Balazs, Banyazs, Tamas, Izu, Leighton T., Chen, Yi-Je, Rajamani, Sridharan, Ginsburg, Kenneth, Bossuyt, Julie, Bers, Donald M., Belardinelli, Luiz, Chen-Izu, Ye

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 86 KB

english, 2014

31

Profile of the Late Sodium Current during Cardiac Action Potential in Guinea Pig Ventricular Cardiomyocytes

Horvath, Balazs, Jian, Zhong, Khabbaz, Shaden, Banyasz, Tamas, Izu, Leighton T., Chen-Izu, Ye

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 40 KB

english, 2012

32

Sarcomere Shortening Destabilizes the Ca2+ Control System in Ventricular Myocytes: Implications for Understanding Arrhythmias in Familial Hypertrophic Cardiomyopathy

Izu, Leighton T., Banyasz, Tamas, Chen-Izu, Ye

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 62 KB

english, 2009

33

Sparklab2: A Statistically Based Program to Detect 2D Sparks. Application to Smooth Muscle

Puglisi, Jose L., Navedo, Manuel, Bers, Donald M., Izu, Leighton T.

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 49 KB

english, 2014

34

Arrhythmogenic Transient Dynamics in Cardiac Myocytes

Xie, Yuanfang, Izu, Leighton T., Bers, Donald M., Sato, Daisuke

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 1.16 MB

english, 2014

35

Increased Myofilament Ca2+ Sensitivity Decreases Sarcomere Length and Increases Spark-Spark Interactions

Chen-Izu, Ye, Banyasz, Tamas, Khabbaz, Shaden, Edelmann, Stephanie, Payne, Charles, Tardiff, Jil C., Izu, Leighton T.

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 81 KB

english, 2011

36

InsP3-Induced Ca2+ Release in Atrial Myocytes

Wullschleger, Marcel, Izu, Leighton T., Egger, Marcel

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 41 KB

english, 2013

37

Mechanical Analysis of Single Myocyte Contraction in a 3D Elastic Matrix

Shaw, John, Izu, Leighton, Chen-Izu, Ye

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 126 KB

english, 2014

38

Transmural Gradient of Ito and INak Profoundly Influence Ventricular Action Potential Duration

Zang, Yunliang, Xia, Ling, Chen-Izu, Ye, Izu, Leighton

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 44 KB

english, 2014

39

Modeling the Dynamic Currents Recorded under Action Potential-Clamp in Cardiac Myocytes

Izu, Leighton T., Banyasz, Tamas, Chen-Izu, Ye

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 42 KB

english, 2010

40

Localized Nitric Oxide Signaling Mediates Cardiac Mechano-Chemotransduction

Jian, Zhong, Han, Huilan, Zhang, Tieqiao, Puglisi, Jose, Izu, Leighton T., Shaw, John, Chen, Yi-Je, Shimkunas, Rafael, Chiamvimonvat, Nipavan, Bers, Donald M., Lam, Kit S., Chen-Izu, Ye

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 42 KB

english, 2014

41

Mechano-Chemotransduction in the Single Cardiac Myocyte Contracting in 3D Elastic Gel

Shimkunas, Rafael, Jian, Zhong, Xiao, Wenwu, Li, Yuanpei, Chen, Yi-Je, Shaw, John, Chiamvimonvat, Nipavan, Izu, Leighton T., Lam, Kit S., Chen-Izu, Ye

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 68 KB

english, 2014

42

Profile of L-type Ca2+ current and Na+/Ca2+ exchange current during cardiac action potential in ventricular myocytes

Banyasz, Tamas, Horvath, Balazs, Jian, Zhong, Izu, Leighton T., Chen-Izu, Ye

Journal:

Year:

2012

Language:

english

File:

PDF, 1.96 MB

english, 2012

43

A modified local control model for Ca2+ transients in cardiomyocytes: Junctional flux is accompanied by release from adjacent non-junctional RyRs

Torres, Natalia S., Sachse, Frank B., Izu, Leighton T., Goldhaber, Joshua I., Spitzer, Kenneth W., Bridge, John H.

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2014

Language:

english

File:

PDF, 1.62 MB

english, 2014

44

Measuring the metrics: Correlating t-tubule structure and muscle contraction in the intact heart

Chen-Izu, Ye, Izu, Leighton T.

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2015

Language:

english

File:

PDF, 172 KB

english, 2015

45

Deranged sodium to sudden death

Clancy, Colleen E., Chen-Izu, Ye, Bers, Donald M., Belardinelli, Luiz, Boyden, Penelope A., Csernoch, Laszlo, Despa, Sanda, Fermini, Bernard, Hool, Livia C., Izu, Leighton, Kass, Robert S., Lederer, W

Journal:

The Journal of Physiology

Year:

2015

Language:

english

File:

PDF, 321 KB

english, 2015

46

Multimodal SHG-2PF Imaging of Microdomain Ca 2+ -Contraction Coupling in Live Cardiac Myocytes

Awasthi, Samir, Izu, Leighton, Mao, Ziliang, Jian, Zhong, Landas, Trevor, Lerner, Aaron, Shimkunas, Rafael, Woldeyesus, Rahwa A, Bossuyt, Julie, Wood, Brittani M, Chen, Yi-Je, Matthews, Dennis L, Lieu

Journal:

Circulation Research

Year:

2015

Language:

english

File:

PDF, 2.41 MB

english, 2015

47

KN-93 inhibits IKr in mammalian cardiomyocytes

Hegyi, Bence, Chen-Izu, Ye, Jian, Zhong, Shimkunas, Rafael, Izu, Leighton T., Banyasz, Tamas

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2015

Language:

english

File:

PDF, 588 KB

english, 2015

48

Determination of the Upper Bound of Intracellular [Na+] by Electrophysiological Method: Probing the Subsarcolemmal [Na+]

Hegyi, Bence, Banyasz, Tamas, Jian, Zhong, Shimkunas, Rafael, Chen-Izu, Ye, Izu, Leighton T.

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 42 KB

english, 2016

49

Mechanical Analysis of Single Myocyte Contraction in a 3D Viscoelastic Gel

Shaw, John A., Wineman, Alan, Shimkunas, Rafael, Izu, Leighton, Chen-Izu, Ye

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 43 KB

english, 2016

50

SHG-2PF Imaging of Local Ca2+ and Sub-Sarcomere Contraction in Live Cardiomyocytes

Awasti, Samir, Izu, Leighton T., Mao, Ziliang, Jian, Zhong, Chen-Izu, Ye, Chan, James W.

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 45 KB

english, 2016

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